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Molecular sieve manufacturer talks about what is the molecular sieve effect

The molecular sieve effect means that when a sample solution containing various molecules slowly flows through a gel chromatography column, each molecule simultaneously stops two different motions within the column: vertical downward motion and non-directional diffusion motion. Because of the larger diameter of macromolecules. In this regard, in order to facilitate everyone's understanding of the relevant operations, the following molecular sieve manufacturer will give a specific description.

It is not easy to enter the micropores of the gel particles, and can only diffuse between particles, so it moves down faster during elution. In addition to diffusing in the pores of the gel particles, small molecules can also move downward in the process of into the micropores of the gel particles, that is, into the gel phase.

Diffusion from one gel to the inter-particle space, then into another gel particle, and then in and out from time to time, the falling rate of small molecular species lags behind that of macromolecular species, so that larger molecules in the sample flow into the spectral column first, and medium molecules The smaller molecules flow out later, and this phenomenon is called the molecular sieve effect.

Molecular sieves have porous gels, and the pore size of various molecular sieves has a certain range, with a larger upper limit and a smaller class limit. If the molecular diameter is larger than the diameter of the larger pores of the gel, they will all be excluded from the gel particles, a situation called total exclusion.


Hunan Providence New Materials Co., Ltd is a professional molecular sieve manufacturer which can provide USY zeolite, NaY zeolite, REY zeolite, ZSM-5 zeolite, welcome to consult.

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